First Patent Issued in Toledo

What is the first patent to issue to a Toledo inventor?  A preliminary search shows U.S. Pat. No. 10,606 issued March 7, 1854 to Chauncey D. Woodruff for an Improved Mode of Suspending Eaves-Troughs.  Is it possible that it took 20 years for a patent to issue to a Toledo inventor after Toledo was founded in 1833?  Was there an earlier one?  What is the most famous patent to issue to a Toledo inventor?  Who is Toledo's most famous inventor?